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- October 31, 2017: An Islamic terrorist drove a truck down a bike path in Manhattan, NYC, NY, resulting in the deaths of 8 people.
- November 5, 2017: A mass shooting occurred at the First Baptist Church in Sutherland Springs, TX, killing 26 people.
- December 28, 2017: A tragic fire broke out in an apartment building in Belmont, Bronx, NY, after a 3-year-old boy played with a stove, leading to 12 deaths.
- December 31, 2017: A plane crash in northwest Costa Rica claimed the lives of 10 U.S. citizens and 2 Costa Rican pilots.
- December 26, 2017 – January 6, 2018: Bitter cold temperatures, ice, and snow caused numerous vehicular accidents across much of the U.S., resulting in 39-40 deaths.
- Winter 2017-2018: The flu season, primarily driven by the H3N2 strain, led to approximately 80,000 deaths.
- January 9, 2018: Heavy rains triggered mudslides and debris flows in Montecito, CA, following forest fires, causing 23 fatalities.
- January 17, 2018: A winter storm brought snow and deep cold across the southern states, resulting in 15 deaths in Georgia, Louisiana, North Carolina, Tennessee, Texas, Virginia, and West Virginia.
- February 14, 2018: A school shooting at Marjory Stoneman Douglas High School in Parkland, FL, claimed 17 lives.
- May 2, 2018: A Puerto Rico Air National Guard C-130 plane crashed near Savannah, GA, killing 9 people.
- May 18, 2018: A school shooting at Santa Fe High School near Houston, TX, resulted in 10 deaths.
- July 13 – September 19, 2018: Wildfires in California, including the Carr Fire, Ferguson Fire, and Mendocino Complex Fire, resulted in 11 deaths.
- July 19, 2018: A duck boat capsized and sank during a storm on Table Rock Lake near Branson, MO, leading to 17 fatalities.
- August 30, 2018: A semitrailer collided with a Greyhound bus after a tire blowout on I-40 near Thoreau, NM, resulting in 9 deaths.
- September 14, 2018: Hurricane Florence made landfall at Wrightsville Beach, NC, with the aftermath impacting North Carolina, South Carolina, and Virginia. The hurricane caused between 55-57 deaths.
- October 2018: An outbreak of Adenovirus 7 at Wanaque Nursing & Rehabilitation Center in Haskell, NJ, led to the deaths of 11 children.
- October 6, 2018: A tragic limousine crash during a birthday party at the Apple Barrel in Schoharie, NY, resulted in 20 deaths.
- October 10, 2018: Hurricane Michael made landfall near Mexico Beach, FL, with additional deaths reported in Georgia, North Carolina, and Virginia, totaling 57-59 fatalities.
- October 27, 2018: A mass shooting at the Tree of Life Synagogue in Pittsburgh, PA, claimed 11 lives.
- November 7, 2018: A mass shooting occurred at the Borderline Bar & Grill in Thousand Oaks, CA, resulting in 13 deaths, including the shooter.
- November 8-11, 2018: Wildfires, especially the Camp Fire in Butte County, CA, led to 88 deaths.
- January 3, 2019: A multi-vehicle collision and diesel fuel fire on I-75 near Gainesville, FL, resulted in 7 deaths.
- January 6, 2019: A drunk driver going the wrong way on I-75 in Lexington, KY, crashed into a car carrying a Michigan family, killing 6 people.
- January 10-13, 2019: Winter Storm Gia caused multiple highway deaths across several states, resulting in 13 fatalities.
- January 28 – February 2, 2019: Polar cold, snow, and ice primarily affected the upper Midwest, causing 30-31 deaths, with most in Illinois.
- February 15, 2019: A workplace shooting in Aurora, IL, resulted in 6 deaths, including the shooter.
- March 3, 2019: Tornadoes, particularly an EF-4 in Lee County, AL, led to 23 fatalities.
- May 31, 2019: A workplace shooting at the Municipal Center Building No. 2 in Virginia Beach, VA, claimed 12 lives.
- June 21, 2019: A skydiving charter plane crash at Dillingham Airfield in Oahu, HI, resulted in 11 fatalities.
- June 21, 2019: A pickup truck crashed into 10 motorcycles on U.S. 2 in Randolph, NH, leading to 7 deaths.
- June 30, 2019: A plane crashed into an Addison, TX hangar shortly after takeoff, resulting in 10 fatalities.
- August 3, 2019: A white supremacist carried out a mass shooting at a Walmart in El Paso, TX, killing 22 people.
- August 4, 2019: A mass shooting outside a bar in Dayton, OH, resulted in 10 deaths, including the shooter.
- August 31, 2019: A shooting rampage in the Midland-Odessa area of TX led to 8 fatalities, including the shooter.
- September 2, 2019: A diving boat caught fire near the north side of Santa Cruz Island, CA, resulting in 34 deaths.
- December 15-16, 2019: A winter storm and icy road conditions caused multiple vehicular crashes across IN, KS, MO, and NE, leading to 12 deaths.
- March 2-3, 2020: Tornadoes, especially in Central TN, including Putnam County, resulted in 24 fatalities.
- April 13, 2020: A series of storms and tornadoes affected multiple states, including LA, AR, MS, GA, SC, NC, and TN, causing 34 deaths.